Parasiticide



Patented Mar. 13, 1934- v UNITED STATES- PATENT OFFICE No Drawing.Application September 9, 1929,

Serial N0. 391,520

2 ohm. (01. 101-21) (Granted llnflel' the act of Match :,1 1883, asamended April so, 192s; 310 o. G. "151) This application is made underthe act approved April 30, 1928, and theinvention herein described, ifpatented, may be manufactured and used by or for the Government forgovernmental purposes without payment to us of any royalty thereon.

We hereby dedicate the invention herein de-, scribed tothe free use ofthe public, to take eflfect upon the granting of a patent to us.

This invention relates to new compositions of matter having for theirobject the utilization of the parasiticidal properties oforthophenylphenol.

The new compositions comprise orthophenylphenol in the free or combinedstate, and a suitable vehicle therefor, and may be used in the solidstate, as a dust or cake, or in the liquid state, as an emulsion orsolution.

We have found that orthophenylphenol possesses marked parasiticida'lpropertiesr Its solubility in water isso low, however, that theseproperties have in the past failed to be observed. .We have found thatorthophenylphenol may be rendered more soluble in water by suitableadmixture with other substances. In suchcompositions of matter it hasmany valuable properties: it is markedly parasiticidal: it has markedantiseptic properties; it is practical and convenient to use; it has noobjectionable odor; it

may be made non-irritating; it has a low toxicity to higher animals; ithas many applications.

A solid preparation may be made in many ways, one of which is by mixingorthophenylphenol with hydrated lime in the form of a white dry powder.

This mixture may be applied .as a parasiticidal white wash. Anotheruseful form is the combination of orthophenylphenol 'orits alkalinesalts with coconut oil soap in the form of a solid or liquid soap using.orthophenylphenol one part and coconut oil soap two to eight parts. Weprefer to use soaps made from cocoanut oil fatty acids, although soapsmade from other materials may also be used. Orthophenylphenol and onepart. A solution of orthophenylphenol may 60 be made in an organicsolvent, as 30% glycerine, in which form it may be used directly on thebody surfaces of higher animals without irritation, or dissolved inanimal, vegetable or mineral oil in which form it may conveniently beused for as internal administration to higher animals. Orthophenyiphenolmay be mixed with alkaline substances or solutions to obtain readilyparasiticidal concentrations when diluted with water.

It is to be understood that while we have here- 70 inbefore givenseveral specific examples of the forms and combinations in whichorthophenylphenol and its alkaline salts may be used as baraslticides,we do not limit ourselves'to such forms and combinations, but desire' itto be un- 15 derstood that orthophenylphenol and its alkaline salts maybe used in many other combinations, too numerous to enumerate, all ofwhich oombinations, even though not specifically described, will beobvious to those skilled in the art to which this invention relates.

As examples of parasites which have been destroyed by dilutions of- 0.2per cent and less of orthophenylphenol in above mentioned compositionsof mattermay be mentioned, bacillus typhosus, staphylococcus aureus,bacillus tuberculosis, lice on hogs, fleas on dogs, etc.

We claim:

1. A parasiticide consisting of orthophenylphenol and coconut oil soapas a solvent for the orthophenylphenol.

2. A parasiticide comprising orthophenylphenol and a solvent thereforcomprising coconut oil soap in an aqueous vehicle.

JACOB M. SCHAI'FER. FRANK W. THEY.

